Chemical synthesis of bioactive peptides &  membrane-associated proteins: from drug discovery to bioinspired materials



20. S. Schöttner, M. Brodrecht, E. Uhlein, C. Dietz, H. Breitzke, A. A. Tietze, G. Buntkowsky,and M. Gallei, Amine-containing block copolymers for the bottom-up preparation offunctional porous membranes, (2019), Macromolecules, 10.1021/acs.macromol.8b02758

19. D. Kaufmann, A. A. Tietze, D. Tietze, In Silico Analysis of the Subtype Selective Blockage of KCNA Ion Channels through the micro-Conotoxins PIIIA, SIIIA, and GIIIA (2019), Marine drugs, 2019, 17

18. Tietze, D.*, Koley Seth, B., Brauser, M., Tietze, A. A., Buntkowsky, G.*, Ni II complex formation and protonation states at the active site of a nickel superoxide dismutase-derived metallopeptide: implications for the mechanism of superoxide degradation (2018), Chemistry,  24, 15879-15888

17. Heimer, P., Tietze, A. A., Bäuml, C. A., Resemann, A., Mayer, F. J., Suckau, D., Ohlenschläger, O., Tietze, D.*, Imhof, D.*, Conformational µ-conotoxin PIIIA isomers revisited: The impact of cysteine pairing on disulfide bond assignment and structure elucidation (2018), Anal. Chem., 90(5), 3321-3327

16. Baumruck, A. C., Tietze, D., Steinacker, L. K., Tietze A. A.*., Chemical synthesis of membrane proteins by native chemical ligation: a model study on the influenza virus B proton channel (2018), Chemical Science, 9, 2365-2375

15. Leipold, E.; Ullrich, F.; Thiele, M.; Tietze, A. A.; Terlau, H.; Imhof, D.; Heinemann, S. H., Subtype-specific block of voltage-gated K+ channels by μ-conopeptides (2017), Biochem. Biophys. Res. Commun, 482 (4), 1135-1140.

14. Baumruck, A. C.; Tietze, D.; Stark, A.; Tietze, A. A., Reactions of Sulfur-Containing Organic Compounds and Peptides in 1-Ethyl-3-methyl-imidazolium Acetate (2017), The Journal of Organic Chemistry, 82 (14), 7538–7545  

13 .Leipold, E., Ullrich, F., Thiele, M., Tietze, A.A., Terlau, H., Imhof, D., Heinemann, S.H.*,
Subtype-specific block of voltage-gated K+ channels by µ-conopeptides (2017), Biochemical and Biophysical Research Communications, 482, 1135-1140.

12. Tietze, D.#, Leipold, E.#, Heimer, P., Böhm, M., Winschel, W., Imhof, D., Heinemann, S.H., and Tietze, A.A.,* Molecular interaction of δ-conopeptide EVIA with voltage-gated Na+ channels, (2016), BBA General Subjects, 1860, 2053-2063

11. Culbertson, A.#, Tietze, A. A.#, Tietze, D., Chou, Y.-H., Smith, A. L., Cook, M. D., Young, Z.T., Zabotina, O. A.*, Homology model of a Xyloglucan Xylosyltransferase 2 reveals critical amino acids involved in substrate binding (2016), Glycobiology, 26(9), 961-972

10. Culbertson, A. T., Chou, Y.-H., Smith, A.L., Young, Z.T., Tietze, A. A., Cottaz, S., Faure, R., Zabotina, O.A.*, Enzymatic Activity of Arabidopsis Xyloglucan Xylosyltransferase 5 (2016), Plant Physiology, 171(3), 1893-904

9. Heimer, P.#, Tietze, A.A.#, Böhm, M.#, Giernoth, R., Kuchenbuch, A., Stark, A., Leipold, E., Heinemann, S.H., Kandt, C., Imhof, D.* Application of room temperature aprotic and protic ionic liquids for exidative folding of cysteine-rich peptides (2015), ChemBioChem 15, 18, 2754–2765  

8. Böhm, M.#, Tietze, A.A.#, Heimer, P.#, Chen, M., Imhof, D.* Ionic liquids as reaction media for oxidative folding and native chemical ligation of cysteine-containing peptides (2014), J. Mol. Liquids, 192, 67-70  

7. Tietze, A.A.*, Bordusa, F., Giernoth, R., Imhof, D., Lenzer, T., Mrestani-Klaus, C., Neundorf, I., Oum, K., Reith, D., Stark, A., On the nature of interactions between ionic liquids and small amino acid-based biomolecules (2013), ChemPhysChem, 14(18), 4044-64  

6. Tietze, A.A., Tietze, D., Ohlenschläger, O., Leipold, E., Ullrich, F., Mischo, A., Buntkowsky, G., Görlach, M., Heinemann, S. H., Imhof, D.*, The one and only fold? Structurally diverse µ-conotoxin PIIIA isomers block sodium channel NaV1.4 (2012), Angew. Chem. Int. Ed., 51 (17), 4058-4061

5. Tietze, A.A.*, Heimer, P., Stark, A., Imhof, D., Ionic liquid applications in peptide chemistry: synthesis, purification and analytical characterization processes (2012), Molecules, 17(4), 4158-4185  

4. Miloslavina, A.A., Ebert, C., Tietze, D., Ohlenschläger, O., Englert, C., Görlach, M., Imhof, D.*, An Unusual Peptide from Conus villepinii: Synthesis, Solution Structure, and Cardioactivity (2010), Peptides, 31, 1292-1300

3. Leipold, E., Markgraf, R., Miloslavina A. A., Kijas M., Schirmeyer, J., Imhof D., Heinemann S. H.*, Molecular determinant for the subtype specificity of µ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels (2010), Neuropharmacology, 61 (1-2), 105-111  

2. Miloslavina, A.A., Leipold E., Kijas M., Stark A., Heinemann S.H., Imhof D.* A room temperature ionic liquid as convenient solvent for the oxidative folding of conopeptides (2009), J. Pept. Sci., 15(2), 72-77  

1. Gotfriedsen, J., Miloslavina, A.A., Edelmann, F. T.*, Cyclooctatetraene made easy (2004), Tetrahedr. Lett., 45, 3583-35