Publications

2025

48. Devrani, S., Tietze, D., Tietze A.A., Automated Microfluidic Platform for High-throughput Biosensor Development, Adv. Biosensor Res., https://doi.org/10.1002/adsr.202400116

47. Hintzen, J.C.J., Rahimi, S., Tietze, D., Zhang, J., Mijakovic, I., Tietze, A.A., Targeted Sortase A Inhibition by Novel Peptidomimetic Antivirulents against Staphylococcal Infections, (2025), bioRxiv, DOI: 10.1101/2025.01.14.632915

2024

46. Abujubara, H., Bharmoria, P., Alvarez, S., Appiah, E., Moth-Poulsen, K., Sayin, V., Tietze, A.A., Transmembrane peptide-loaded ionic liquid nanocarriers for targeting ErbB2-positive cancer, (2024), ChemRxiv, DOI: 10.26434/chemrxiv-2024-wkw04

45. Mueller, L., Zhdanova, H., Unksov, I., Gräwe, A., Stahl, J., Stein, V., Tietze, D., Tietze, A.A., DNA scission of non-His-containing ATCUN-like peptides (2024), ChemRxiv, DOI: 10.26434/chemrxiv-2024-ds4gr

44. Serna-Cardona, N. J., Zamora-Leiva, L. G., Sánchez-Carvajal, E., Claverías, F. P., Cumsille, A. I., Pentón, K. A., Vivanco, B., Tietze, A., Tessini, C., Cámara, B. P., Unveiling Metabolo-genomic Insights of Potent Antitumoral and Antibiotic Activity in Streptomyces sp. VB1 from Valparaíso Bay (2024), Front. Microbiol., Sec. Antimicrobials, Resistance and Chemotherapy, 15, DOI: 10.3389/fmicb.2024.1463911

43. Hintzen, J.C.J, Devrani, S., Carrod, A.J., Bayik, M.B., Tietze, D., Tietze, A.A. Fluorescent labeling of ATCUN-like peptides for application in Cu(II)-sensing, Fluorescence Labeling of Peptides: Finding the Optimal Protocol for Coupling Various Dyes to ATCUN-like Structures (2024), ACS Org. Inorg. Au, DOI: 10.1021/acsorginorgau.4c00030

42. Hintzen, J. C. J., Abujubara, H., Tietze, D., Tietze, A. A., The complete assessment of small molecule and peptidomimetic inhibitors of Sortase A towards antivirulence treatment (2024), Chem. Eur. J., DOI: 10.1002/chem.202401103

41. Eisenhauer, K., Weber, W., Kemp, P., Gebhardt, C., Kaufmann, M., Tewes, N., Zhdanova, H., Tietze, A., Rauh, O., Stein, V., Scaling the Functional Nanopore (FuN) Screen: Systematic Evaluation of Self-Assembling Membrane Peptides and Extension with a K+-Responsive Fluorescent Protein Sensor (2024), ACS Synth. Biol., 13, 4, 1382-1392, DOI: 10.1021/acssynbio.3c00671

40. Bharmoria, P., Tietze, A., Mondal, D., Kang, T., Kumar, A., Freire, M., Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment (2024), Chem. Rev., 124, 6, 3037–3084, DOI:10.1021/acs.chemrev.3c00551

39. Valli, D., Ooi, S. A., Scattolini, G., Chaudhary, H., Tietze, A.A., Maj, M., Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins (2024), Biophys. J., 123, 6, 718-729, DOI: 10.1016/j.bpj.2024.02.009

38. Beyer, L., Schäfer, A.-B., Undabarrena, A., Mattsby-Baltzer, I., Tietze, D., Svensson, E., Stubelius, A., Wenzel, M., Camara, B., Tietze, A. A., Mimicking Non-ribosomal Peptides from the Marine Actinomycete Streptomyces sp. H-KF8 Leads to Antimicrobial Peptides (2024), ACS Infect. Dis., 10, 1, 79-92, DOI: 10.1021/acsinfecdis.3c00206

2023

37. Abujubara, H.; Hintzen, J. C. J.; Rahimi, S.; Mijakovic, I.; Tietze, D.; Tietze, A. A.,* Substrate-derived Sortase A Inhibitors: Targeting an Essential Virulence Factor of Gram-positive Pathogenic Bacteria (2023), Chem. Sci., DOI: 10.1039/D3SC01209C

36. Bharmoria, P.;* Ooi, S. A.; Cellini, A.; Tietze, D.; Maj, M.; Moth-Poulsen, K.;* Tietze, A. A.,* Protein Cohabitation: Long-term Immunoglobulin G Storage at Room Temperature (2023), J. Mater. Chem. B, DOI: 10.1039/D3TB00161J

35. Abujubara, H., Yang, J., Otyakmaz, B., Noisier, A. F. M., Czechtizky, W., Lemurell, M. and Tietze, A. A.,* Ionic liquid-mediated approach for the synthesis of site-specific thioether conjugates (2023), Chem. Eur. J., e202203915, DOI: 10.1002/chem.202203915

2022

34. Weber, W., Roeder, M., Abujubara, H., Koeppl, H., Tietze, A. A., Stein, V. The functional nanopore (FuN) screen: a versatile genetic assay to study and engineer protein nanopores in Escherichia coli. (2022), ACS Synth. Biol.,11, 6,2020-2079, DOI: 10.1021/acssynbio.1c00635

2021

33. Duznovic, I., Gräwe, A., Weber, W., Müller, L. K., Ali, M., Ensinger, W., Tietze, A., Stein, V., Ultrasensitive and Selective Protein Recognition with Nanobody-Functionalized Synthetic Nanopores. (2021), Small, 17, 33, 2101066, DOI: 10.1002/smll.202101066

32. Baumruck, A. C., Yang, J., Thomas, G.-F., Beyer, L. I., Tietze, D., Tietze, A. A.*, Native chemical ligation of highly hydrophobic peptides in ionic liquid-containing media. (2021), J. Org. Chem., 86 (2), 1659-1666, DOI: 10.1021/acs.joc.0c02498

31. Montoliu Gaya, L., Tietze, D., Kaminski, D., Mirgorodskaya, E., Tietze, A. A., Sterky, F.,* CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway (2021), EMBO Reports, DOI: 10.15252/embr.202051349

2020

30. Belyaeva, V.S., Stepenko, Y.V., Lyubimov, I.I., Kulikov, A.L., Tietze, A. A., Kochkarova, I.S., Martynova, O.V., Pokopeyko, O.N., Krupen'kinam l.A., Nagikh, A.S., Pokrovskoy, V.M., Patrakhanov, E.A., Belashova, A.V., Lebedev, P.R., Gureeva, A.V.,* Non-hematopoietic erythropoietin-derived peptides for atheroprotection and treatment of cardiovascular diseases (2020), Research Results in Pharmacology, 6(3), 75-86

29. Müller, L.K.#, Duznovic, I.#, Tietze, D., Weber, W., Ali, M., Stein, V., Ensinger, W., Tietze, A. A.*, Ultrasensitive and selective copper (II) detection: introducing a bioinspired and robust sensor (2020), Chem. Eur. J., 26 (39), 8511-8517, DOI: 10.1002/chem.202001160

28. Müller, L. K., Baumruck, A. C., Zhdanova, H., Tietze, A. A.*, Challenges and perspectives in chemical synthesis of highly hydrophobic peptides (2020), Front. Bioeng. Biotechnol., 8, 162, DOI: 10.3389/fbioe.2020.00162

2019

27. Korokin, M. V., Soldatov, V. O., Tietze, A. A., Golubev, I. V., Kubekina, M. V., Puchenkova, O. A., Denisyuk, T. A., Gureyev, V. V., Pokrovskaya, T. G., Gudyrev, O. S., Zhuchenko, M. A., Zatolokina, Pokrovskiy, M. V. 11-amino acid peptide imitating the structure of erythropoietin α-helix b improves endothelial function, but stimulates thrombosis in rats (2019), Pharmacy & Pharmacology, 7(6):312-320

26. Tietze, D.*, Batzer-Kaufmann, D., Tietze, A. A., Voll, A., Reher, R., Koenig, G. M., Hausch, F. Structural and dynamical basis of G protein inhibition by YM-254890 and FR900359: an inhibitor in action (2019), J. Chem. Inf. Model., 59 (10), 4361-4373

25. Schöttner, S., Brodrecht, M., Uhlein, E., Dietz, C., Breitzke, H., Tietze, A. A., Buntkowsky, G. and Gallei, M. Amine-containing block copolymers for the bottom-up preparation offunctional porous membranes (2019), Macromolecules, 52, 7, 2631-2641

24. Kaufmann, D. , Tietze, A. A., Tietze, D. In Silico Analysis of the Subtype Selective Blockage of KCNA Ion Channels through the micro-Conotoxins PIIIA, SIIIA, and GIIIA (2019), Marine Drugs, 17 (3), 180

2018
23. Tietze, D.*, Koley Seth, B., Brauser, M., Tietze, A. A., Buntkowsky, G.*, Ni II complex formation and protonation states at the active site of a nickel superoxide dismutase-derived metallopeptide: implications for the mechanism of superoxide degradation (2018), Chemistry, 24, 15879-15888

22. Heimer, P., Baeuml, C.A., Schmitz, T., Resemann, A., Mayer, F.J., Suckau, D., Tietze, A., Ohlenschläger, O., Tietze, D., Imhof, D., Impact of cysteine pairing on disulfide-bond assignment and structure elucidation in different conformational isomers of the µ-conotoxin PIIIA (2018), J. Pept. Sci., 24, S154

21. Steinacker, L., Baumruck, A., Tietze, A.A. Development of a strategic and quantitative route for the chemical synthesis of membrane-associated proteins (2018), J. Pept. Sci., 24, S100

20. Weissheit, S., Kahse, M., Kämpf, K., Tietze, A., Vogel, M., Winter, R., Thiele, C.M., Elastin-like peptide in confinement: FT-IR and NMR T1 relaxation data (2018), Z. Phys. Chem., 232, 7-8, 1239

19. Heimer, P., Tietze, A. A., Bäuml, C. A., Resemann, A., Mayer, F. J., Suckau, D., Ohlenschläger, O., Tietze, D.*, Imhof, D.*, Conformational µ-conotoxin PIIIA isomers revisited: The impact of cysteine pairing on disulfide bond assignment and structure elucidation (2018), Anal. Chem., 90(5), 3321-3327

18. Baumruck, A. C., Tietze, D., Steinacker, L. K., Tietze A. A.*., Chemical synthesis of membrane proteins by native chemical ligation: a model study on the influenza virus B proton channel (2018), Chem. Sci., 9, 2365-2375

2017
17. Leipold, E., Ullrich, F., Thiele, M., Tietze, A. A., Terlau, H., Imhof, D., Heinemann, S. H., Subtype-specific block of voltage-gated K+ channels by μ-conopeptides (2017), Biochem. Biophys. Res. Commun, 482 (4), 1135-1140.

16. Baumruck, A. C., Tietze, D., Stark, A., Tietze, A. A., Reactions of Sulfur-Containing Organic Compounds and Peptides in 1-Ethyl-3-methyl-imidazolium Acetate (2017), J. Org. Chem., 82 (14), 7538–7545

15. Culbertson, A.T., Tietze, A., Smith, A., Zabotina, O., Three-dimensional structure of Xyloglucan Xylosyltransferase I and proposed methanism of catalysis (2017), FASEB J., 31, 951.4

2016
14. Tietze, D.#, Leipold, E.#, Heimer, P., Böhm, M., Winschel, W., Imhof, D., Heinemann, S.H., and Tietze, A. A.*, Molecular interaction of δ-conopeptide EVIA with voltage-gated Na+ channels, (2016), BBA Gen. Sub., 1860, 2053-2063

13. Culbertson, A.#, Tietze, A. A.#, Tietze, D., Chou, Y.-H., Smith, A. L., Cook, M. D., Young, Z.T., Zabotina, O. A.*, Homology model of a Xyloglucan Xylosyltransferase 2 reveals critical amino acids involved in substrate binding (2016), Glycobiology, 26(9), 961-972

12. Culbertson, A. T., Chou, Y.-H., Smith, A.L., Young, Z.T., Tietze, A. A., Cottaz, S., Faure, R., Zabotina, O.A.*, Enzymatic Activity of Arabidopsis Xyloglucan Xylosyltransferase 5 (2016), Plant Physiol., 171(3), 1893-904

2015
11. Heimer, P.#, Tietze, A. A.#, Böhm, M.#, Giernoth, R., Kuchenbuch, A., Stark, A., Leipold, E., Heinemann, S.H., Kandt, C., Imhof, D.* Application of room temperature aprotic and protic ionic liquids for exidative folding of cysteine-rich peptides (2015), Chem. Biol. Chem. 15, 18, 2754–2765

2014
10. Böhm, M.#, Tietze, A. A.#, Heimer, P.#, Chen, M., Imhof, D.* Ionic liquids as reaction media for oxidative folding and native chemical ligation of cysteine-containing peptides (2014), J. Mol. Liquids, 192, 67-70

2013
9. Tietze, A. A.*, Bordusa, F., Giernoth, R., Imhof, D., Lenzer, T., Mrestani-Klaus, C., Neundorf, I., Oum, K., Reith, D., Stark, A., On the nature of interactions between ionic liquids and small amino acid-based biomolecules (2013), Chem. Phys. Chem., 14(18), 4044-64

8. Tietze, A. A., Tietze, D., Ohlenschläger, O., Ullrich, F., Leipold, E., Heinemann, S.H., Imhof, D., Structurally diverse isomers of a pharmaceurically interesting µ-conotoxin (2013), Biopolymers, 100(3), 260-261

2012
7. Tietze, A. A., Tietze, D., Ohlenschläger, O., Leipold, E., Ullrich, F., Mischo, A., Buntkowsky, G., Görlach, M., Heinemann, S. H., Imhof, D.*, The one and only fold? Structurally diverse µ-conotoxin PIIIA isomers block sodium channel NaV1.4 (2012), Angew. Chem. Int. Ed., 51 (17), 4058-4061

6. Tietze, A. A.*, Heimer, P., Stark, A., Imhof, D., Ionic liquid applications in peptide chemistry: synthesis, purification and analytical characterization processes (2012), Molecules, 17(4), 4158-4185

2010
5. Miloslavina, A. A., Ebert, C., Tietze, D., Ohlenschläger, O., Englert, C., Görlach, M., Imhof, D.*, An Unusual Peptide from Conus villepinii: Synthesis, Solution Structure, and Cardioactivity (2010), Peptides, 31, 1292-1300

4. Miloslavina, A. A., Stark, A., Imhof, D., Bioactive cysteine-rich peptides are interesting targets for oxidative folding and native chemical ligation in ionic liquids (2010), J. Pept. Sci., 16, 75

3. Leipold, E., Markgraf, R., Miloslavina A. A., Kijas M., Schirmeyer, J., Imhof D., Heinemann S. H.*, Molecular determinant for the subtype specificity of µ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels (2010), Neuropharm., 61 (1-2), 105-111

2009
2. Miloslavina, A. A., Leipold E., Kijas M., Stark A., Heinemann S.H., Imhof D.* A room temperature ionic liquid as convenient solvent for the oxidative folding of conopeptides (2009), J. Pept. Sci., 15(2), 72-77

2004
1. Gotfriedsen, J., Miloslavina, A. A., Edelmann, F. T.*, Cyclooctatetraene made easy (2004), Tetrahedr. Lett., 45, 3583-35

#-EQUAL CONTRIBUTION
*-CORRESPONDING AUTHOR